Showing posts with label World. Show all posts
Showing posts with label World. Show all posts

Herbal Viagra actually contains the real thing



































IF IT looks too good to be true, it probably is. Several "herbal remedies" for erectile dysfunction sold online actually contain the active ingredient from Viagra.












Michael Lamb at Arcadia University in Glenside, Pennsylvania, and colleagues purchased 10 popular "natural" uplifting remedies on the internet and tested them for the presence of sildenafil, the active ingredient in Viagra. They found the compound, or a similar synthetic drug, in seven of the 10 products – cause for concern because it can be dangerous for people with some medical conditions.












Lamb's work was presented last week at the American Academy of Forensic Sciences meeting in Washington DC.












This article appeared in print under the headline "Herbal Viagra gets a synthetic boost"


















































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Smartphone projector breathes life into storybooks



Hal Hodson, technology reporter



Remember your favourite storybook from childhood? Now imagine that the characters that graced its pages didn't only appear in print, but acted out scenes right in front of you, à la magic Harry Potter paintings.


HideOut, a smartphone projector system developed by Karl Willis at Disney Research in Pittsburgh, Pennsylvania, does exactly that by using invisible-ink markers to guide the projected characters of a storybook through an entire other layer of activities.






The projector also lets the user move a digital, animated character over surfaces in the real world. By passing the camera over another of the hidden patterns - which are visible only in infrared - the character can even seem to interact with physical obstacles, as in the video above.


In a paper describing the system, presented this month at the Tangible, Embedded and Embodied Interaction conference in Barcelona, Spain, Willis laid out how projection will move past games and playing to become an important computer-human interaction technology, freeing digital content from the screens.


Willis writes that future smartphones with embedded projectors will be used to browse digital files projected on any wall or table, to augment theme parks with digital characters, or to make digital board games that jump out of the table. "Enabling projected content to be mapped onto everyday surfaces from mobile devices is an important step towards seamless interaction between the digital and physical worlds."




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Canine intelligence tests reveal how dogs think



Sandrine Ceurstemont, editor, New Scientist TV






Think your dog is smarter than most? Now you can put the pooch through a series of science-based tests that reveal its cognitive style.







Developed by Brian Hare from Duke University in Durham, North Carolina, and colleagues, a new website called Dognition allows dog owners to see how their pets fare in experiments exploring memory skills, cunning, empathy and even knowledge of physics. In this video, a dachshund and a mixed breed visit the New Scientist office to pit their wits against the games. Each dog often responds differently to cues from its owner: Ginny the dachshund, for example, was reluctant to disobey her owner when her back was turned, whereas Leicester, our other dog subject, immediately steals the treat.



The team will be using the information gathered through the website to gain a better understanding of how dogs think. By using "citizen science", they can quickly get large amounts of data compared with conducting the research themselves.



Hare is interested in the behaviour of domestic dogs because it gives insight into our own evolution. "The dog is the only species we've found that has some of the communicative skills that look like what infants need to acquire language and culture," he says. Canines learn words by inference, much like human babies, and can read their owners' gestures, something that even chimps and bonobos are incapable of. For more on the human-dog connection, check out our interview with Hare, "Old dog tricks: The survival of the friendliest".



If you enjoyed this post, meet a dog with the vocabulary of a 3-year-old or watch a dog determine which human will be most generous with treats.




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US research to be put online for free



































YOU paid for it, so you should be able to see it. On Sunday the US government said that all federally funded research results must be available for free online. The UK made a similar decision last year.












Most research papers are behind paywalls. Now all federal agencies that spend $100 million annually on research and development will have to make their results freely available by a specified time after initial publication. The US government suggests 12 months as a suitable delay. According to John Holdren, director of the US Office of Science and Technology Policy, this will improve access to information while still allowing publishers to charge for early access.











The movement towards open access has been accelerating. Last July the UK government announced that all publicly funded research will be available for free starting in 2014. Furthermore, 13,000 researchers are boycotting the academic publisher Elsevier – owned by the same company as New Scientist – in protest at its high prices.













This article appeared in print under the headline "Science free for all"


















































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Vulcan and Cerberus win popular Pluto moon-naming vote



Jacob Aron, reporter


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First contact any time now (Image: CBS via Getty)


Nearly half a million votes are in, and Vulcan and Cerberus are the most popular names for the fourth and fifth moons of Pluto - currently known as P4 and P5.


The team that discovered the two moons asked the public to vote on 12 potential names, including Cerberus. But they also accepted write-in votes as long as they were taken from Greek and Roman mythology and related to Hades and the underworld - keeping to the theme used to name Pluto's three other moons.






"We have been overwhelmed by the world's response," says Mark Showalter of the SETI Institute in Mountain View, California, who led the discovery of P4 and P5.


Despite not being on the original list of 12, Vulcan is most popular with nearly 175,000 votes. The name was originally suggested by Star Trek actor William Shatner, in honour of a planet from the show. It just about fits the criteria: in Roman mythology, Vulcan, the god of lava and smoke, is Pluto's nephew. "Any connection to the Star Trek TV series is purely coincidental," Showalter said at the time

Cerberus got the second slot with just under 100,000 votes, while the next
favourite, Styx, trailed with fewer than 88,000. Showalter and the team
will now present the names to the International Astronomical Union,
which has final approval. If the IAU decides to
reject either name, it won't be the first time it has gone against
public opinion on Pluto - there were mass demonstrations following the union's decision to demote it to dwarf-planet status in 2006.


"Please
be patient now," says Showalter. "It could take one to two months for the
final names of P4 and P5 to be selected and approved. Stay tuned."




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Armband adds a twitch to gesture control

















































And you thought depth-sensing cameras were cool: well, now there's a gesture control device that looks like a sweatband. It lets you control everything from computers to flying drones just by moving the muscles in your forearm.












The Myo, built by Canadian startup firm Thalmic Labs, based in Kitchener, Ontario, aims to bring gestural interfaces right into the mainstream. Electrodes embedded in the band read electrical activity in a user's muscles as they contract or relax to make gestures with their hand and arm, and transmit it wirelessly to software that interprets the movements into commands.












"We really have this belief that technology can be used to enhance our abilities," says Stephen Lake, co-founder of Thalmic Labs. "This is a way of using natural actions that we've evolved to intuitively control the digital world."












Lake and his team built Myo using electrodes that work without making direct contact with the skin, unlike medical electrodes. The first generation can recognise around 20 gestures, some as subtle as the tap of a finger – and it is programmed to ignore random noise generated by other body movements.












Myo's creators envision it as an easy way to interact with everything from web browsers to video games to small drones. The first generation of the product, is expected to cost $149 and ship later this year. It will come with software that will allow any Windows or Apple Mac machine to recognise the gestures we use on touchscreens – like a vertical swipe to scroll down a page, or a pinch to zoom.












"It's not very often that a new, affordable and convenient interface technology comes along, so I think a lot of programmers are going to want to try it," says Trevor Blackwell, founder of robotics company Umbrella Research and a partner in Y Combinator. This startup incubator programme is based in Mountain View, California and has provided Thalmic Labs with funding in exchange for a 7 per cent stake in the company. "I think so far we've only thought of around 1 per cent of its potential applications."











Thalmic Labs is not the first firm to try making a device that recognises gestures by sensing muscle activity. In 2008, Microsoft created a prototype called MUCI that worked in a similar fashion to Myo, but needed medical electrodes, which are not feasible outside of a laboratory setting.












There are also devices that use cameras to precisely track users' hand motionsMovie Camera, but they are either in early stages of development, or not portable. "Maybe this couldn't have been foreseen by early researchers working with cameras, but people don't like having cameras watching them all the time," Blackwell says. "Thalmic solves that problem nicely." Though the first generation of Myo is only just launching, the team is already imagining ways to integrate their rigs with augmented reality devices like the head-mounted display, Google Glass.













"If they combined with Google's Project Glass, I think it would be huge," says computer scientist Shahzad Malik, who co-founded the software company CognoVision of Toronto. "Something like Thalmic's technology is super-useful since you can do interactions in a subtle way, which is important when you're in a public venue."












"We're interested in seeing just how closely we can integrate technology into our daily lives and give people superpowers, if you like," says Lake.




















Wear tech... look great?







Making wearable technology fashionable is tough – think belt-mounted cellphones, beepers, and bluetooth ear pieces. But iPod earbuds and headphones seem to work.









How do you get the mix right? Google is working hard to make Project Glass rigs look hip, even convincing clothing designer Diane von Fürstenberg and her models to wear prototypes of the head-mounted displays at Fashion Week in New York last year.









Myo bands (see main story) could be an easier sell , says computer scientist Shahzad Malik. "I could see these bands becoming smaller and smaller, or are made in different colours. Or there could be clothing with it built in," he says.









































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New blood test finds elusive fetal gene problem



































A NEW non-invasive blood test for pregnant women could make it easier to catch abnormalities before their child is born.












Human cells should have two copies of each chromosome but sometimes the division is uneven. Existing tests count the fragments of placental DNA in the mother's blood. If the fragments from one chromosome are unusually abundant, it might be because the fetus has an extra copy of that chromosome. But triploidy, where there are three copies of every chromosome, is missed, since the proportion of fragments from each chromosome is the same.












California-based company Natera uses an algorithm to calculate the most likely genotype for the fetus. To do this it looks at single letter variations called SNPs in the parents and compares this to a database of the most common SNPs patterns in the population. This genotype is then compared with placental DNA.












This approach can catch triploidy since the whole fetal genotype is the reference rather than a single chromosome. The method was presented last week at the Society for Maternal-Fetal Medicine in San Francisco.












This article appeared in print under the headline "No hiding place for fetal gene errors"


















































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Amazon to open market in second-hand MP3s and e-books






















A new market for second-hand digital downloads could let us hold virtual yard sales of our ever-growing piles of intangible possessions






















WHY buy second-hand? For physical goods, the appeal is in the price – you don't mind the creases in a book or rust spots on a car if it's a bargain. Although digital objects never lose their good-as-new lustre, their very nature means there is still uncertainty about whether we actually own them in the first place, making it tricky to set up a second-hand market. Now an Amazon patent for a system to support reselling digital purchases could change that.












Amazon's move comes after last year's European Union ruling that software vendors cannot stop customers from reselling their products. But without technical support, the ruling has had no impact. In Amazon's system, customers will keep their digital purchases – such as e-books or music – in a personal data store in the cloud that only they can access, allowing them to stream or download the content.












This part is like any cloud-based digital locker except that the customer can resell previous purchases by passing the access rights to another person. Once the transaction is complete, the seller will lose access to the content. Any system for reselling an e-book, for example, would have to ensure that it is not duplicated in the transaction. That means deleting any copies the seller may have lying around on hard drives, e-book readers, and other cloud services, since that would violate copyright.












Amazon may be the biggest company to consider a second-hand market, but it is not the first. ReDigi, based in Boston, has been running a resale market for digital goods since 2011. After downloading an app, users can buy a song on ReDigi for as little as 49 cents that would costs 99 cents new on iTunes.












When users want to sell an item, they upload it to ReDigi's servers via a mechanism that ensures no copy is made during the transfer. Software checks that the seller does not retain a copy. Once transferred, the item can be bought and downloaded by another customer. ReDigi is set to launch in Europe in a few months.












Digital items on ReDigi are cheaper because they are one-offs. If your hard drive crashes and you lose your iTunes collection you can download it again. But you can only download an item from ReDigi once – there is no other copy. That is the trade-off that makes a second-hand digital market work: the risk justifies the price. The idea has ruffled a few feathers – last year EMI sued ReDigi for infringement of copyright. A judge denied the claim, but the case continues.


















Used digital goods can also come with added charm. ReDigi tracks the history of the items traded so when you buy something, you can see who has owned it and when. ReDigi's second-hand marketplace has grown into a social network. According to ReDigi founder John Ossenmacher, customers like seeing who has previously listened to a song. "It's got soul like an old guitar," he says. "We've introduced this whole feeling of connectedness."












It could be good for business too if the original vendors, such as iTunes, were to support resale and take a cut of the resell price. Nevertheless, Amazon's move bucks the industry trend. Microsoft's new Xbox, for example, is expected not to work with second-hand games.












But the market could change rapidly now that Amazon's weight is behind this, says Ossenmacher. "The industry is waking up."












This article appeared in print under the headline "Old MP3, one careful owner"




















































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Desperate data about desperate children



Shaoni Bhattacharya, consultant


109276917.jpg

A 13-year-old girl, Aissata Konate, a few days after getting married to 32-year-old Ely Barry in Gbon, Ivory Coast (Image: Carol Guzy/The Washington Post/Getty)


If governments could pass a simple law that would save the lives of millions of infants, they’d do it, right? And if a policy or constitution could transform the lives of women by sparing them the poor health or despair that they inevitably pass on to their children through sickness, disability, and even death, surely they would get working?


But no.


A new book, the first of its kind, together with the extensive report underpinning it, shows just how far the world has to go - even (or perhaps, especially) rich countries like the US.


Children’s Chances: How countries can move from surviving to thriving by Jody Heymann with Kristen McNeill was launched (with the accompanying report) in London last week. It aims to provide an armoury of deeply disturbing data with which to hold to account the world’s passive politicians.





It is a culmination of years of work led by Heymann, who is director of the World Policy Analysis Center and dean of the University of California, Los Angeles, Fielding School of Public Health.


She and her colleagues have sifted through (quite literally sometimes) boxes piled with paper and reams of information from organisations like UNESCO to provide the first global comparison of laws and public policies in 191 countries covering poverty, discrimination, education, health, child labour, child marriage and parental care options.


Laws really matter, found Heymann and her colleagues. Laws covering what look to be family or cultural decisions such as early child marriage or education are important because these issues determine whether a child survives or thrives.


When girls marry young, for example, they tend to drop out of school earlier and have poorer health, and, in turn, their children have poorer health.


At the book’s launch at the Royal Society in London Heymann said that sometimes just having a law can help: “What surprised me is that many people had said, 'What if policies are not fully implemented?' In fact many of these policies are so powerful that it is enough [to make a difference].”


The book, report and website aim to make the crucial information Heymann and her colleagues have gathered accessible to ordinary citizens, non-governmental organisations and policy-makers.


It’s readable, and given the Herculean task the authors had bringing it all together, makes clear sense of what they found with online maps providing a wealth of revealing information never before available, at a keystroke.


But I can’t help feeling that they are missing a trick. The tone of the book may be assertive, but it is not as forceful as its material - just too polite.


Why beat about the bush when children’s lives, health and future are at risk? Name and shame, I say. This book has the moral high ground, and scientific rigour, to do so. And it should.


At the launch, the US was rightly described as a “laggard”, but it is only by trawling through the maps that it becomes clear just how far behind it is for a rich nation.


What, for example, does the US have in common with Papua New Guinea, Liberia and Tonga?


These are three of only eight countries in the world with no guaranteed paid maternity leave. As for paternity leave, paid parental leave for sick children - forget it.


And there isn’t even protection against early child marriage. The US is right up there with Sudan and Iran, with no legal minimum age for marriage for girls or boys.


This was shocking, but the authors don’t go into surprises like this. Surely we should be told what the lack of such a law does to a developed nation like the US? Does anyone actually get married very young? If so, how young, and how common is it?


But we do know that lack of maternity leave makes a huge difference. Globally every 10-week increase in paid maternity is associated with a 10 per cent drop of newborn deaths, infant deaths and under-5 mortality rates. Staggering.


The reasons are simple. Off work, mothers are more likely to breastfeed and take their babies to be vaccinated.


Even in the US, infant mortality rates are not good for a developed nation. And recent studies show the country’s health generally is not as robust as it could be.


There are plenty of other surprises.


What does Laos do for its children that the UK doesn’t? Astonishingly, it is one of five countries in the world with father-specific paid paternity leave of over four weeks. The others are Iceland, Norway, Slovenia and Sweden.


Luxury? No. Paternity leave matters and when it's specifically allocated to men, dads are more likely to take it. Studies show that fathers who take paternity leave when it is available are much more involved with care of their children, even after a pre-existing commitment to mother and child is controlled for.


And where fathers are involved, new mothers are less likely to get depressed - and maternal depression has strong knock-on effects on children.


Then again, what makes one of the poorest African nations a better place to be a child than its neighbours? Madagascar has policies for children and families that are more progressive than many western nations, and this has paid off because its infant and child mortality rates are among the lowest in sub-Saharan Africa.


Sadly, the most powerful of the emerging economies - India and China - fare worse than many very poor countries in terms of children’s chances and healthcare.


The authors want this to be a call for action. But they need to shout louder. While they do quote the numbers of countries opting out of child-friendly policies or laws in their report, they should name the countries - and give them a report card. And likewise hail the countries (especially the poor ones) doing right by their kids.


The book does try quite hard in some ways, detailing heart-rending case studies of kids so hungry that they fall asleep at school, 9-year-olds rising at 4 am to help their parents set up street vegetable stalls before going to school, or parents who can’t take seriously ill kids to the doctor because they risk losing their jobs if they take time off…


The good news is that governments can move mountains if they find the will: saving the lives of millions of children worldwide is surely easy compared with finding a cure for AIDS or cancer?


Heymann and colleagues should be commended for their meticulous and arduous work. Let’s hope citizens, NGOs and movers and shakers pick up this report and wield it forcefully in the faces of governments.



Book information:
Children’s Chances: How countries can move from surviving to thriving by Jody Heymann
with Kristen McNeill
Harvard University Press
$45/£33.95

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First space tourist plans independent Mars mission



Jacob Aron, reporter


rexfeatures_336719a.jpg

(Image: Sipa/Rex)


An organisation led by Dennis Tito, the first ever space tourist, has announced its intention to launch a mission to Mars in 2018 - though just who or what will be on board remains to be seen.





Tito paid $20 million to be the first paying guest of the International Space Station in 2001, marking the start of the space tourism industry. Now he has formed the Inspiration Mars Foundation, which plans to launch "an historic journey to Mars and back in 501 days", according to an announcement in advance of a press conference next Wednesday.


The announcement does not give many more details of the mission, but other speakers lined up for the press conference give some clues. Jonathan Clark of the National Space Biomedical Research Institute in Houston, Texas, a former NASA crew surgeon and recent advisor on Felix Baumgartner's supersonic skydive from near the edge of space, will probably speak about the health risks of a long-term space mission, which hints at the possibility of a crewed mission.


Also speaking are Jane Poynter and Taber MacCallum of Paragon Space Development, a company with expertise in life support in extreme environments. The pair were both members of the Biosphere 2 mission, a controversial attempt at simulating a space colony two decades ago, and have previously proposed landing a greenhouse on the moon to grow flowers there.


Speculation ahead of the announcement is rife. Wired reckons the mission will aim to be crewed. NBC
is more cautious, suggesting that the plan might be to put plants or animals on board
instead, as pulling a crewed mission together in five years would be
expensive and risky. The 2018 date is particularly favourable because the
orbits of Earth and
Mars will be closely aligned, but NASA recently scrubbed a launch that
year in favour of a 2020 sequel to its successful Curiosity rover. Bottom line: it's hard to get to Mars in a hurry.


We
also don't know whether the mission is meant to land on Mars or
merely orbit the planet. Space Adventures, which booked Tito's ISS
trip, has been selling moon fly-bys since 2005, though none has taken place so far. But even an uncrewed return mission to the surface of the Red Planet would make history if it brought Mars rocks back to Earth.


Also
to be announced is just how Tito plans to get to Mars. The obvious
answer is to use Space X's Red Dragon craft, a planned variant of the
Dragon capsule that has already serviced the ISS. Space X founder Elon Musk has promised to deliver humans to Mars within a decade, so five years might be slightly short notice. We'll find out more on 27 February.




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Harness vast power of quantum computers… for sums



































Quantum computers sound exotic but their power may lie in solving mundane equations – fast.











Until now these systems have been geared towards tasks such as factorising huge numbers, which would not be much use outside cryptography.













In 2009, Seth Lloyd at the Massachusetts Institute of Technology and colleagues devised a quantum algorithm for solving systems of linear equations, such as determining two unknown variables that appear in two separate equations. This example is classroom algebra, but scale it up to millions of variables and the same mathematics drives weather forecasting, image processing and traffic analysis.












Lloyd's team showed that while the number of steps in the classical algorithm scales with the number of equations, for the quantum version, it scales with the logarithm of that number – equivalent to solving a trillion equations in a few hundred steps.











Entangled implementation













"You basically take a classical algorithm that sucks and do it in quantum parallel," says Lloyd, taking advantage of the fact that a quantum computer can perform multiple calculations at the same time.












Now Stefanie Barz's team at the University of Vienna, Austria, has got Lloyd's algorithm working on a very simple quantum computer, using two entangled photons to solve a system of two equations (arxiv.org/abs/1302.1210). Though too simple to be useful in itself, it is a neat demonstration. "It is very nice that they've been able to implement it," says Lloyd.











Meanwhile, Jiangfeng Du's team at the University of Science and Technology of China, Hefei, has demonstrated Lloyd's algorithm with a four-equation system (arxiv.org/abs/1302.1946). But they used a quantum computer based on the spins of atomic nuclei that some physicists fear won't scale.



















































If you would like to reuse any content from New Scientist, either in print or online, please contact the syndication department first for permission. New Scientist does not own rights to photos, but there are a variety of licensing options available for use of articles and graphics we own the copyright to.




































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Moody Mercury shows its hidden colours



Jacob Aron, reporter


600px_messenger_orbit_image20130218_1_4by3_946-710.jpg

(Image: NASA/Johns Hopkins University Applied Physics Laboratory/Carnegie Institution of Washington)


It might look like poor old Mercury is feeling a bit blue, but fear not - these are false-colour images produced by NASA's Messenger space probe.


To the human eye, the closest planet to the sun is covered in a dull mottling of brown-grey splodges. Filtering the light from its surface lets researchers see chemical, mineralogical and physical differences in the planet's rocks that will help us understand its history and evolution.


In this view, white and light blue streaks show lines of material thrown up and spread across the surface by relatively recent impacts. Deep blue regions are rich in an as-yet unknown mineral, while the orange spots correspond to ancient volcanic plains.


Cheer up, Mercury, it's not that bad!





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Oil spill firm to pay $400 million to fix Gulf coast









































The Deepwater Horizon spill has just provided a $400-million windfall for Louisiana's environment. Transocean, which worked with BP on the stricken Macondo well, pleaded guilty last week to a violation of the US Clean Water Act, and admitted that it was negligent in the 2010 spill. The resulting multimillion-dollar fine will be used to pay for a host of environmental projects around the Gulf of Mexico.











It is the second largest fine for environmental damage in history, after the $4.5-billion fine BP had to pay out for the same spill. Transocean has two years to pay up in full.













The National Academy of Sciences (NAS) will get $150 million, and another $150 million will go to the National Fish and Wildlife Foundation (NFWF), a non-profit based in Washington DC. The NAS will use its portion to research oil-spill prevention and better ways to respond to spills. The NFWF's Timothy DiCintio says it will distribute its award between the affected Gulf Coast states, for ongoing remediation efforts such as marsh and wetland clean-up.











The remainder of the money will go directly to Louisiana's $50-billion Coastal Master Plan, which aims to restore the state's degraded coastline. The money will fund a host of projects, including restoring barrier island reefs and creating diversions on the Mississippi to repair eroded coasts.













"The way Louisiana looks at it, their coastal problems are so pervasive that the degradation from the spill was a final indignity," says DiCintio. The modifications should not only allow the state to rebuild after the lingering effects of the spill and hurricane Katrina, but also help the coast cope with future disasters.


















































If you would like to reuse any content from New Scientist, either in print or online, please contact the syndication department first for permission. New Scientist does not own rights to photos, but there are a variety of licensing options available for use of articles and graphics we own the copyright to.




































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False memories prime immune system for future attacks









































IN A police line-up, a falsely remembered face is a big problem. But for the body's police force – the immune system – false memories could be a crucial weapon.












When a new bacterium or virus invades the body, the immune system mounts an attack by sending in white blood cells called T-cells that are tailored to the molecular structure of that invader. Defeating the infection can take several weeks. However, once victorious, some T-cells stick around, turning into memory cells that remember the invader, reducing the time taken to kill it the next time it turns up.












Conventional thinking has it that memory cells for a particular microbe only form in response to an infection. "The dogma is that you need to be exposed," says Mark Davis of Stanford University in California, but now he and his colleagues have shown that this is not always the case.












The team took 26 samples from the Stanford Blood Center. All 26 people had been screened for diseases and had never been infected with HIV, herpes simplex virus or cytomegalovirus. Despite this, Davis's team found that all the samples contained T-cells tailored to these viruses, and an average of 50 per cent of these cells were memory cells.












The idea that T-cells don't need to be exposed to the pathogen "is paradigm shifting," says Philip Ashton-Rickardt of Imperial College London, who was not involved in the study. "Not only do they have capacity to remember, they seem to have seen a virus when they haven't."












So how are these false memories created? To a T-cell, each virus is "just a collection of peptides", says Davis. And so different microbes could have structures that are similar enough to confuse the T-cells.












To test this idea, the researchers vaccinated two people with an H1N1 strain of influenza and found that this also stimulated the T-cells to react to two bacteria with a similar peptide structure. Exposing the samples from the blood bank to peptide sequences from certain gut and soil bacteria and a species of ocean algae resulted in an immune response to HIV (Immunology, doi.org/kgg).












The finding could explain why vaccinating children against measles seems to improve mortality rates from other diseases. It also raises the possibility of creating a database of cross-reactive microbes to find new vaccination strategies. "We need to start exploring case by case," says Davis.












"You could find innocuous pathogens that are good at vaccinating against nasty ones," says Ashton-Rickardt. The idea of cross-reactivity is as old as immunology, he says. But he is excited about the potential for finding unexpected correlations. "Who could have predicted that HIV was related to an ocean algae?" he says. "No one's going to make that up!"












This article appeared in print under the headline "False memories prime our defences"




















































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False memories prime immune system for future attacks









































IN A police line-up, a falsely remembered face is a big problem. But for the body's police force – the immune system – false memories could be a crucial weapon.












When a new bacterium or virus invades the body, the immune system mounts an attack by sending in white blood cells called T-cells that are tailored to the molecular structure of that invader. Defeating the infection can take several weeks. However, once victorious, some T-cells stick around, turning into memory cells that remember the invader, reducing the time taken to kill it the next time it turns up.












Conventional thinking has it that memory cells for a particular microbe only form in response to an infection. "The dogma is that you need to be exposed," says Mark Davis of Stanford University in California, but now he and his colleagues have shown that this is not always the case.












The team took 26 samples from the Stanford Blood Center. All 26 people had been screened for diseases and had never been infected with HIV, herpes simplex virus or cytomegalovirus. Despite this, Davis's team found that all the samples contained T-cells tailored to these viruses, and an average of 50 per cent of these cells were memory cells.












The idea that T-cells don't need to be exposed to the pathogen "is paradigm shifting," says Philip Ashton-Rickardt of Imperial College London, who was not involved in the study. "Not only do they have capacity to remember, they seem to have seen a virus when they haven't."












So how are these false memories created? To a T-cell, each virus is "just a collection of peptides", says Davis. And so different microbes could have structures that are similar enough to confuse the T-cells.












To test this idea, the researchers vaccinated two people with an H1N1 strain of influenza and found that this also stimulated the T-cells to react to two bacteria with a similar peptide structure. Exposing the samples from the blood bank to peptide sequences from certain gut and soil bacteria and a species of ocean algae resulted in an immune response to HIV (Immunology, doi.org/kgg).












The finding could explain why vaccinating children against measles seems to improve mortality rates from other diseases. It also raises the possibility of creating a database of cross-reactive microbes to find new vaccination strategies. "We need to start exploring case by case," says Davis.












"You could find innocuous pathogens that are good at vaccinating against nasty ones," says Ashton-Rickardt. The idea of cross-reactivity is as old as immunology, he says. But he is excited about the potential for finding unexpected correlations. "Who could have predicted that HIV was related to an ocean algae?" he says. "No one's going to make that up!"












This article appeared in print under the headline "False memories prime our defences"




















































If you would like to reuse any content from New Scientist, either in print or online, please contact the syndication department first for permission. New Scientist does not own rights to photos, but there are a variety of licensing options available for use of articles and graphics we own the copyright to.




































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Russian meteor will teach us about future bigger hits

















































You wait years for a space rock and then two come along at once. Just hours before an asteroid is due to almost graze Earth, a meteor has exploded over the Russian region of Chelyabinsk, injuring hundreds of people and damaging nearby buildings.











Studying the impact could give clues to future hits from rarer, bigger space rocks, which are bound to occur.












The impact occurred at 0320 GMT today, the very day that astronomers are anticipating the close fly-by of asteroid 2012 DA14, although there is thought to be no connection between the two events. "This is a remarkable coincidence," says Stephen Lowry, an astronomer at the University of Kent in Canterbury, UK.













Details of the strike are still emerging, but pictures and video shared on social media offer clues to the meteor's make-up and origin. "It's certainly smaller than 50 metres and larger than a metre," says Simon Green of the Open University in Milton Keynes, UK. It appears to have exploded as it entered the Earth's atmosphere, creating a shock wave that shattered windows, damaged buildings and apparently collapsed the roof and walls of zinc factory.












The Russian Academy of Sciences says the meteor weighed 10 tons and entered the atmosphere at a speed of at least 54,000 kilometres per hour, exploding between 30 to 50 kilometres above the ground. Reports from Russia also say that more than 900 hundred people have been injured, mostly by broken glass. Reports also suggest there are no fatalities, although two people are in intensive care.











Astronomers will want to recover any fragments of the meteorite that hit the ground. "You'll find them strewn over a large area. There may be some very large fragments but there will be many smaller ones spread over kilometres," says Green. "We can study the science of the bodies and learn more about the bigger ones, which are the real threat."












The much smaller Sutter's Mill meteorite that fell on California last year yielded many fragments that showed it was a very rare type of rock called a CM chondrite.












Strange coincidence













It is not unusual for meteors the size of the one that fell in Chelyabinsk to hit the Earth, though most end up falling into the sea unnoticed. "Depending on its size, it might be something that hits every few years or every few decades," says Green.












Although the odds of an unrelated meteor impacting on the same day as an asteroid fly-by seem astronomically high, experts seem sure the two objects are not linked, especially as the meteor hit over 12 hours before the expected fly-by. "2012 DA14 approaches from the south at quite a steep angle relative to the Earth's equatorial plane, so Russia being in the northern hemisphere makes [a link] extremely unlikely," says Lowry. "If this had been a southern hemisphere impact, serious questions would have been being asked."












One of the European Space Agency's satellites managed to spot the vapour trail of the meteor as it entered the atmosphere. The agency itself has also confirmed that there is no link with asteroid 2012 DA14, on course to fly past Earth at height of around 27,000 kilometres at 1925 GMT.












There are a large number of videos of the Russian meteor strike because it is common for Russian drivers to use dashboard-mounted cameras to prove liability in car accidents. The footage should allow astronomers to retrace the meteor's flight path and identify its origin, as well as any other space rocks that might be related. One possibility is that the meteor split off from a larger object. "It is possible that a collision could have happened further back in its orbit," says Lowry.












If the remnants remained on the same orbit, then they too could impact Earth, although that is unlikely as the planet has most likely moved out of the path of any potential secondary strike by now. "It is possible a parent fragment could hit Earth, but the probability decreases rapidly as time passes."












Read more: Meteorite hunters: Join the space rock rush


















































If you would like to reuse any content from New Scientist, either in print or online, please contact the syndication department first for permission. New Scientist does not own rights to photos, but there are a variety of licensing options available for use of articles and graphics we own the copyright to.




































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How Facebook makes breaking up hard to do



Paul Marks, senior technology reporter


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(Image: Andy Kingsbury/Corbis)


I am not particularly prone to earbugs, but Jimmy Ruffin's emotive Motown classic What Becomes of the Brokenhearted began playing in my mind when I came across this intriguingly titled research paper last week: "Design for forgetting: Disposing of digital possessions after a breakup".


Yes, I know it’s Valentine’s Day, and love is in the air. For people who have recently suffered a break-up, though, it’s a tough day to get through - and this research shows how social technologies are making it tougher still. It asks if the "huge collections of digital possessions" couples now acquire in latter-day, online-social-media-rich relationships make breaking up, er, hard to do.


It seems it does, as Corina Sas at Lancaster University in the UK and Steve Whittaker of the University of California, Santa Cruz, are due to tell a computer interaction conference - which, appropriately, takes place in April in Paris. The pair asked 24 people who had recently split with their lovers how they dealt with the digital detritus of their affair - texts, emails, music, video clips, Facebook messages or photos - stored across multiple gadgets, from computers to mobile phones, cameras and even digital picture frames.





Perhaps not too surprisingly they found their subjects developed a variety of "digital disposal" strategies, depending on the degree of hurt. That has led the researchers to suggest ways in which the likes of Facebook could develop novel features to help newly split couples better manage what they call "digital forgetting".


The 24 subjects revealed three main break-up strategies, Sas says: "Some people tended to keep too much digital content, leaving them subjected to painful reminiscences. Others impulsively deleted digital possessions they may later want. Still others engaged in immediate discontinued use and later selective disposal."


Whittaker adds: "Many people make multiple mistakes when they dispose of digital possessions: some immediately delete too impulsively but later regret not keeping stuff."


Your digital relationship is more difficult to dispose of than burning love letters in days of yore, and your Twitters and Facebooks are the major bugbear. The relationship traces we leave on social networking systems "could be particularly difficult to remove and emotionally taxing when accidentally revisited", Sas says.


"Some of the greatest problems related to interactions and content in Facebook where couples were constantly reminded of their ex. Unless they unfriend them, partners could easily see what the ex is up to."


To the rescue, of course, comes even more technology.


Sas and Whittaker would like to see Facebook offer more "couple-oriented" features that make it easier to erase a couple's joint content later - a kind of digitally mediated pre-nup. That might get over the problem of having relationship material present on other friends’ pages, outside your control but still visible to you.


They also propose development of - and get this for ambition - automatic relationship-information harvesting software. "This tool would gather together all the digital possessions relating to the ex in one place. At the moment possessions are spread across laptops, phones, Facebook, et cetera, so it's hard to hide or delete everything about the ex," says Whittaker.


They realise this is no trivial task - but it's worth the effort, they believe. Automatically hoovering up a couple's digital pictures, emails and text messages would require a raft of artificial-intelligence techniques, from face recognition to machine learning and "entity extraction". "That would generate a unified set of digital possessions that can be later dealt with appropriately," says Sas.


In the meantime, her advice is to quell the red mist re the digital stuff post break-up. "Keeping or deleting everything may be tempting, but acting on such impulses may not the best approach in the long run. Instead try to create some immediate distance from digital possessions and revisit them later to choose only the most memorable ones." Rather like putting your old photos in a tin until you’ve cooled off, then.


If not, to quote Jimmy Ruffin, "all that's left is an unhappy ending".



Paper reference: Proceedings of the 2013 Conference on Human factors in Computing Systems (in press)




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US begins to batten down the cyber hatches at last



Paul Marks, chief technology correspondent


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(Image: Ulrich Baumgarten via Getty Images)


It's not often that a US government spokesman is left speechless. But when we called the Department of Homeland Security in September 2009 to ask them about the fact that Chinese engineers had published details on how to bring down the US power grid, the initial silence down the line spoke volumes about the gravity of the matter.

Now President Barack Obama has decided to do something about the severe cyberthreat posed to critical US infrastructure, from power grids to gas pipelines, water reservoirs, dams and the telecommunications networks that underpin both commerce and, indeed, our digitally dependent lifestyles.





"Now our enemies are also seeking the ability to sabotage our power grid, our financial institutions and our air-traffic control systems, we cannot look back years from now and wonder why we did nothing," the president said in his State of The Union address last night.


So in an executive order he signed yesterday, Obama instructed companies running critical US infrastructure to join an experimental programme in which they will share threat information with each other and with government on the kind of cyberattacks they are dealing with day to day. The broad-brush aim will be to develop meaningful - and agile - defences that can be used across different infrastructure types, with standards agreed by the National Institute of Standards and Technology.


The order will enforce a new level of collaboration between the US director of national intelligence (who runs the 16 intelligence-gathering arms of the government), the Department of Homeland Security and the firms at the helm of essential utilities. Details are scant - the US Department of Commerce is expected to reveal more later today - but a White House fact sheet says that one thorny complicating factor will be the "multinational ownership" of many such firms, making information-sharing potentially risky.


Obama's move echoes the situation in the UK, where GCHQ - the latter-day heirs of Alan Turing's Bletchley Park codebreakers - work alongside the Ministry of Defence and the Centre for the Protection of National Infrastructure to identify infrastructural and criminal cyberthreats, with the aim of giving "the UK the balance of advantage in cyberspace". However, a UK National Audit Office report issued this week revealed that the UK's chronic cyber-skills shortage (the last government taught schoolchildren Excel and PowerPoint instead of computer programming, Google famously noted) will make it tough to fight the online battle adequately for at least 20 years.


This is a particular shame in the light of the fact that the digital forensics experts at the CrySys Lab in Budapest, Hungary, last week revealed that it is indeed possible to reprogram the powerful Stuxnet, Flame and Duqu malware packages that were released to - among other unknown infrastructure targets - attack Iran's nuclear programme. And who oversaw the release of these potent cyberweapons that anyone can now reprogram? Step forward, Barack Obama.




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Latest Landsat in 40-year mission blasts off



Jacob Aron, reporter


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(Image: GSFC/NASA)


Up, up and away! The Landsat Data Continuity Mission, the newest addition to NASA's 40-year mission monitoring Earth from space, blasted into orbit atop this Atlas V rocket yesterday. The successful launch ensures observations will continue uninterrupted once the LDCM satellite's predecessor, Landsat 7, runs out of fuel in 2016.



The two satellites take pictures in both visible and infrared light, and also track changes in the Earth's temperature, providing data for everything from Google Maps to climate science. The Landsat programme has also given us a couple of past Pictures of the Day: the impact of deforestation in Brazil and the path of a tornado in Massachusetts. By April, the LDCM satellite should have reached a polar orbit 705 kilometres up.





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Can the internet revive US democracy?



Jim Giles, consultant



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Tech-savvy campaigns get mixed results, as the Arab Spring shows (Image: William Dupuy/Picturetank)



Gavin Newsom's Citizenville shows that technology can empower people, but the book fails to explore deep-rooted problems within the democratic process



THERE'S a lot of crime in Oakland, California. But until a few years ago, citizens had little way of assessing the scale of the problem. Then Michal Migurski hurt his back. It was Christmas 2006 and Migurski, a computer programmer, was stuck at home in Oakland, looking for ways to use his time until his back healed. He knew about the area's crime problem and decided to create an online map showing where and when crimes had been committed - something local government had failed to do.



Migurski's crimespotting.org website gets enthusiastic coverage in Gavin Newsom's Citizenville, a homage to technology's ability to empower people and reform government. If committed and skilled citizens like Migurski can access official data, for example, they can create services that governments don't have time for or aren't well equipped to provide. The internet has already disrupted a swathe of industries, from journalism to telecommunications. Citizenville is packed with examples that show that it is government's turn.





citizenville_cover.jpg

For the book, Newsom - California's lieutenant governor - talked to a host of Silicon Valley luminaries, from Google founder Sergey Brin to Tim O'Reilly, tech publisher and one of the most high-profile advocates of the idea that technology can transform government. The result is a 239-page tribute to what the valley does best: suggest radical and scalable ways to do things better.



Unfortunately, Newsom's unfettered enthusiasm for the power of the internet and smartphones to transform social and governmental problems makes for a shallow read. Take his analysis of FarmVille, the incredibly successful Facebook game in which players run virtual farms. Why couldn't a similar game be used to help govern a real city, he asks? It's an intriguing idea, based in part on the argument put forward by Jane McGonigal, a game designer, that gaming can be used to solve real-world problems.



But doesn't FarmVille's appeal have much to do with its lack of real-life responsibility? Newsom only touches on this before rushing off to his next tech-inspired solution.



It's a frustrating approach because Newsom was mayor of San Francisco between 2003 and 2010, and rolled out some bold tech-based reforms during his tenure, so he is well placed to discuss the benefits and difficulties of applying technology to governance.



Some of the most interesting parts of Citizenville address ideas that did not work, like radical transparency. After becoming mayor, Newsom decided to post his diary on the web, until his chief of staff pointed out that fundraising meetings would be visible. Newsom relented, accepting that voters don't like to see politicians asking for money.



It's a great example of how technology is just part of the reform equation. To truly empower, technology will have to deal with many entrenched problems, ranging from the shameless distortions that most elected officials spout to the huge number of alienated people who don't register to vote. Any proper assessment of technology's power to change needs to do more than consider the solutions it offers. The impoverished democratic process in the US will not improve until the causes of this situation are part of the discussion.



Broader initiatives exist, of course. Political scientists who study how misinformation spreads have teamed up with technologists to create systems for reining in erroneous memes, like the claim that Barack Obama is not a US citizen. Public health experts are studying not just the internet's ability to communicate health information but also the extent to which that information changes behaviour. It is this kind of thinking, which accepts that technology is only part of the solution, that is missing from Citizenville. I was left wishing that Newsom had focused on just a few of the issues he writes about, and had taken his research beyond the confines of Silicon Valley.



This article appeared in print under the headline "There is no app for political reform"



Book information:
Citizenville: How to take the town square digital and reinvent government by Gavin Newsom and Lisa Dickey
Penguin
$25.95

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